Making insulin producing beta cells from stem cells – how close are we?

Two recent studies have revealed for the first time how to generate insulin producing cells resembling normal beta cells, in the lab, from human pluripotent stem cells. This provides a step forward for a potential cell therapy treatment for diabetes. But how alike are these cells to the beta cells found in our bodies? How close are we to testing these cells in diabetics? And what other questions still remain? In this commentary, HumEn Project Co-ordinator Henrik Semb tackles these questions providing perspective in this complex and challenging field. Read the full commentary here